GENE365 GENERAL AND MOLECULAR GENETICS
| Course Code: | 2190365 |
| METU Credit (Theoretical-Laboratory hours/week): | 4 (4.00 - 0.00) |
| ECTS Credit: | 6.0 |
| Department: | Molecular Biology and Genetics |
| Language of Instruction: | English |
| Level of Study: | Undergraduate |
| Course Coordinator: | Prof.Dr. AYŞE ELİF ERSON BENSAN |
| Offered Semester: | Fall Semesters. |
Course Objectives
By the end of the course, the student will have learned:
- the fundamentals of transmission genetics, and the molecular, developmental and evolutionary mechanisms behind these;
- the basic processes in molecular genetics; including the structure of DNA, mechanisms of DNA replication, transcription, translation, and gene expression regulation;
- current problems, terminology, and technology in the field of genetics.
Course Content
In this course general principles of Mendelian Genetics, chromosome theory of heredity, linkage and mapping, structure and function of both prokaryotic and eukaryotic genes, gene expression and its regulation, changes in genetic material, chromosomal aberrations and mutations are covered. Elementary principles that govern developmental, quantitative, population and evolutionary genetics are included. Fundamentals of recombinant DNA technology are also included from a biotechnological perspective. The course has been designed for the students of Molecular Biology & Genetics Program.
Course Learning Outcomes
The successul student will be able to:
- describe the basic laws and mechanisms governing transmission genetics;
- predict inheritance modes by studying pedigrees;
- describe the fundamental processes in molecular genetics, including DNA replication, mutation, recombination, transcription, and translation;
- distinguish between prokaryotic and eukaryotic systems with respect to gene regulation;
- suggest experiments to study alternative mechanisms of gene regulation;
- develop hypotheses on the molecular, developmental and evolutionary mechanisms behind specific inheritance patterns;
- understand the specific uses of recombinant DNA and genomics technologies;
- develop realistic research strategies to genetic study of phenotypic variation and disease, including evolutionary differences among species, hereditary disease, pathogenic disease, cancer, and aging;
- discuss the potential social implications of genetic technologies;
- start reading primary genetic literature.
Program Outcomes Matrix
| Level of Contribution | |||||
| # | Program Outcomes | 0 | 1 | 2 | 3 |
| 1 | Apply the most advanced and current experimental techniques in genetic engineering, molecular biology and molecular genetics | ✔ | |||
| 2 | Practice and defend the work safety rules | ✔ | |||
| 3 | Have a commend of scientific processes; critique; design experiments and ask questions leading to theorizing | ✔ | |||
| 4 | Communicate in English and Turkish with high proficiency | ✔ | |||
| 5 | Read and interpret the current worldwide literature in molecular biology and genetics | ✔ | |||
| 6 | Pursue the most recent advances in molecular biology and genetics; explain and relate the advances to colleagues | ✔ | |||
| 7 | Challenge technical and technological riddle and welcome life-long education | ✔ | |||
| 8 | Work individually or as a team member, easily start and propagate brain storm in a work group | ✔ | |||
| 9 | Employ and defend scientific ethic rules and make them motto for their team | ✔ | |||
0: No Contribution 1: Little Contribution 2: Partial Contribution 3: Full Contribution