CHEM531 REACTIVE INTERMEDIATES I
| Course Code: | 2340531 |
| METU Credit (Theoretical-Laboratory hours/week): | 3 (3.00 - 0.00) |
| ECTS Credit: | 8.0 |
| Department: | Chemistry |
| Language of Instruction: | English |
| Level of Study: | Graduate |
| Course Coordinator: | |
| Offered Semester: | Fall Semesters. |
Course Objectives
Course Objectives
1) Gain insight about what reactive intermediates are understand the concept of reactive intermediates in correlation with reaction coordinate diagrams
2) Gain insight about the structure and reactivity of carbocations. Students should comprehend the methods for generation of carbocations and should develop deep understanding in possible outcomes of their reactions.
3) Gain insight about the structure and reactivity of carbanions. Students should comprehend the methods for generation of carbanions and should develop deep understanding in possible outcomes of their reactions
4) Gain insight about the structure and reactivity of carbon radicals. Students should comprehend the methods for generation of carbon radicals and should develop deep understanding in possible outcomes of their reactions.
5) Gain insight about the structure and reactivity of nitrenes. Students should comprehend the methods for generation of nitrenes and should develop deep understanding in possible outcomes of their reactions.
6) Gain insight about the structure and reactivity of several reactive intermdiates such as benzyne, oxonium ions, certain ylide structures, certain halonium ions and reactive oxygen species. Students should comprehend the methods for generation of these compounds and should develop deep understanding in possible outcomes of their reactions.
Course Content
Carbonise: structure and reactivity, generation of carbones, cycloadditionreactions of carbones, insertion and rearrangement, synthetic application. Nitrenes: generation insertions of nitrenes and rearrangement and synthetic application. Singlet oxygen: generation, reaction of singlet oxygen, chemistry of bicyclic endoperoxides. Consent of the department reaction mechanism in organic chemistry is strongly recommended.
Course Learning Outcomes
Describe the different methods available for carbocation generation Describe general patterns of reactivity of carbocations. Describe the different methods available for carbanion generation Describe general patterns of reactivity of carbanion. Describe the different methods available for carbon radical generation Describe general patterns of reactivity of carbon radicals. Describe the different methods available for carbon radical generation Describe general patterns of reactivity of carbon radicals. Describe the different methods available for nitrene generation
10)Describe general patterns of reactivity of nitrenes.
11) Describe the different methods available for generation of various other reactive intermediates such as benyznes, oxonium ions, certain ylide structures, certain halonium ions and reactive oxygen species.
12) Describe general patterns of reactivity of various other reactive intermediates such as benyznes, oxonium ions, certain ylide structures, certain halonium ions and reactive oxygen species.
Program Outcomes Matrix
| Level of Contribution | |||||
| # | Program Outcomes | 0 | 1 | 2 | 3 |
| 1 | Graduates of the Chemistry master program can follow scientific literature as well as developments in technology. | ✔ | |||
| 2 | Our graduates have critical, analytical and independent thinking abilities. | ✔ | |||
| 3 | They have the ability of working independently. | ✔ | |||
| 4 | They have ability to analyze and solve problems. | ✔ | |||
| 5 | They scientifically contribute to the areas that they have expertise on. | ✔ | |||
| 6 | They have the background to pursue their PhD in both national and international universities. | ✔ | |||
| 7 | They can perform team work. | ✔ | |||
| 8 | They can have active roles in interdisciplinary studies with researchers from different backgrounds. | ✔ | |||
| 9 | They have the ability to interpret the data obtained from interdisciplinary studies and contribute to the existing knowledge. | ✔ | |||
| 10 | They have the leadership ability to solve challenges that are faced during the projects. | ✔ | |||
| 11 | They have the ability to present their work orally and in a written text as scientific papers or reports. | ✔ | |||
| 12 | They can speak and write English which is the scientific language. | ✔ | |||
| 13 | They can use the communication technologies to transfer their results. | ✔ | |||
| 14 | They are aware of the ethical values during their studies and transfer their results to scientific society. | ✔ | |||
0: No Contribution 1: Little Contribution 2: Partial Contribution 3: Full Contribution