GENE745 EPIGENETIC MECHANISMS OF CELL FATE

Course Code:2190745
METU Credit (Theoretical-Laboratory hours/week):3 (3.00 - 0.00)
ECTS Credit:8.0
Department:Molecular Biology and Genetics
Language of Instruction:English
Level of Study:Graduate
Course Coordinator:Assoc.Prof.Dr. NİHAL TERZİ ÇİZMECİOĞLU
Offered Semester:Spring Semesters.

Course Objectives


Course Content

Epigenetic control of pluripotency, reprogramming and transdifferentiation; Epigenetic regulation of embryonic stem cell differentiation, adult and cancer stem cells; epigenetic mechanisms during development; regulation of gene expression on chromatin level; eukaryotic genomic DNA packaging; post-translational modification of nucleosomes.


Course Learning Outcomes


Program Outcomes Matrix

Level of Contribution
#Program Outcomes0123
1Explain the inner workings of the scientific process, discuss critically, and solve problems by applying appropriate statistical and computational methods; choose contemporary experimental and theoretical approaches in molecular biology and genetics.
2Communicate issues in both English and Turkish with high proficiency.
3Read, and critique scientific communications in molecular biology and molecular genetics literature with worldwide recognition.
4Identify and explain issues in molecular biology and genetics within the context of other disciplines.
5Readily apply innovative theoretical and technological challenges acting upon the need for lifelong learning.
6Produce data and interpret results as an individual, as well as a team player, and lead whenever necessary.
7Apply and defend the rules of scientific ethics within their careers and professions.

0: No Contribution 1: Little Contribution 2: Partial Contribution 3: Full Contribution