GENE553 INTEGRATED SIGNAL TRANSDUCTIONS: CONCEPTS AND APPROACHES

Course Code:2190553
METU Credit (Theoretical-Laboratory hours/week):3 (3.00 - 0.00)
ECTS Credit:8.0
Department:Molecular Biology and Genetics
Language of Instruction:English
Level of Study:Graduate
Course Coordinator:Prof.Dr. MESUT MUYAN
Offered Semester:Fall Semesters.

Course Objectives


Course Content

The lecture is intended to provide an integrated perspective how various signal transduction circuits sense, amplify, and integrate extracellular signals to generate responses reflected as changes in enzyme activities, gene expressions and protein properties that affect cellular proliferation, growth, motility and death. The course introduce important classes of molecules in primary axial systems, specifically hypothelamo-hypophyseal-gonadal axis, that participate, and cross-talk, in signal-transduction pathways. The course also review how alterations in signaling circuits lead to pathologies and approaches to counter them. The course is critical in providing an outlook for interdisiplinary subjects that include biotechnology and biomedical engineering.


Course Learning Outcomes


Program Outcomes Matrix

Level of Contribution
#Program Outcomes0123
1Explain the inner workings of the scientific process, discuss critically, and solve problems by applying appropriate statistical and computational methods; choose contemporary experimental and theoretical approaches in molecular biology and genetics.
2Communicate issues in both English and Turkish with high proficiency.
3Read, and critique scientific communications in molecular biology and molecular genetics literature with worldwide recognition.
4Identify and explain issues in molecular biology and genetics within the context of other disciplines.
5Readily apply innovative theoretical and technological challenges acting upon the need for lifelong learning.
6Produce data and interpret results as an individual, as well as a team player, and lead whenever necessary.
7Apply and defend the rules of scientific ethics within their careers and professions.

0: No Contribution 1: Little Contribution 2: Partial Contribution 3: Full Contribution