GENE434 GENE REGULATION: TRANSCRIPTIONAL PERSPECTIVE
| Course Code: | 2190434 |
| METU Credit (Theoretical-Laboratory hours/week): | 3 (3.00 - 0.00) |
| ECTS Credit: | 6.0 |
| Department: | Molecular Biology and Genetics |
| Language of Instruction: | English |
| Level of Study: | Undergraduate |
| Course Coordinator: | Prof.Dr. SEMRA KOCABIYIK, Prof.Dr. AYŞE GÜL GÖZEN, Assoc.Prof.Dr. NİHAL TERZİ ÇİZMECİOĞLU |
| Offered Semester: | Fall and Spring Semesters. |
Course Objectives
Provide understanding of gene regulation phenomena and its impact on cellular functions,
Prepare students for further study in Molecular Genetics and Life Sciences,
Encourage students to be involved in research on the hot topics of gene regulation
Course Content
The course deals with the mechanistic analysis of transcriptional and post-transcriptional processes involved in the controlling gene expression in eukaryotes, including the basic mechanisms of gene activation and repression, epigenetic modifications, chromatin remodeling machines and mechanisms, regulation of transcription activation by signal transduction cascades, mechanisms regulating RNA and the role of noncoding RNAs in gene regulation. The current topics on the role of gene regulation in specific biological processes and human diseases will also be discussed.
Course Learning Outcomes
Learn fundamental concepts necessary for thoughtful understanding of the transcription regulatory mechanisms.
Acquaint her/himself with the current regulatory mechanisms with a focus on eukaryotic systems
Examine and interpret the manisfestations of different control mechanisms and impacts of aberrant control.
Program Outcomes Matrix
| Level of Contribution | |||||
| # | Program Outcomes | 0 | 1 | 2 | 3 |
| 1 | Apply the most advanced and current experimental techniques in genetic engineering, molecular biology and molecular genetics | ✔ | |||
| 2 | Practice and defend the work safety rules | ✔ | |||
| 3 | Have a commend of scientific processes; critique; design experiments and ask questions leading to theorizing | ✔ | |||
| 4 | Communicate in English and Turkish with high proficiency | ✔ | |||
| 5 | Read and interpret the current worldwide literature in molecular biology and genetics | ✔ | |||
| 6 | Pursue the most recent advances in molecular biology and genetics; explain and relate the advances to colleagues | ✔ | |||
| 7 | Challenge technical and technological riddle and welcome life-long education | ✔ | |||
| 8 | Work individually or as a team member, easily start and propagate brain storm in a work group | ✔ | |||
| 9 | Employ and defend scientific ethic rules and make them motto for their team | ✔ | |||
0: No Contribution 1: Little Contribution 2: Partial Contribution 3: Full Contribution