EE415 INTRODUCTION TO MEDICAL IMAGING

Course Code:5670415
METU Credit (Theoretical-Laboratory hours/week):3 (3.00 - 0.00)
ECTS Credit:5.0
Department:Electrical and Electronics Engineering
Language of Instruction:English
Level of Study:Undergraduate
Course Coordinator:Prof.Dr. NEVZAT GÜNERİ GENÇER
Offered Semester:Fall Semesters.

Course Objectives

By the end of the course the students will be able to comprehend  the fundamentals of four major medical imaging modalities, namely, X-ray  CT and digital radiography, magnetic resonance imaging, ultrasound and radionuclide imaging, PET and SPECT.

 


Course Content

Fundamentals of X-ray, generation and detection of X-rays, X-ray diagnostic methods, X-ray image characteristics, biological effects of ionizing radiation. Fundamentals of acoustic propagation, generation and detection of ultrasound, ultrasonic diagnostic methods, biological effects of ultrasound. Fundamentals of radionuclide imaging, generation and detection of nuclear emission, radionuclide imaging methods, radiation dosimetry and biological effects. Fundamentals of magnetic resonance imaging, generation and detection of NMR signal, imaging methods, biological effects of magnetic fields.


Course Learning Outcomes

Student, who passed the course satisfactorily will be able to:

  • understand the fundamentals of basic X-ray imaging methods
    • distinguish different forms of interactions between X-rays and matter,
    • define X-ray intensity and attenuation,
    • understand the basic operation principles of X-ray generators, filters, beam restrictors and grids, intensifying screens, fluorescent screens, and X-ray films,
    • understand the operation of X-ray radiography, fluoroscopy, angiography, mammograph, and conventional tomography
    • express the relation between projections and attenuation distribution of the body given the source and detector configuration, 
    • implement different image reconstruction algorithms (backprojection, filtered backprojection, fourier domain approach using central slice theorem) for computerized tomography 
    • explain and calculate X-ray image characteristics (spatial resolution, image noise, image contrast)
    • comprehend the biological effects of ionizing radiation.
  • understand the fundamentals of nuclear medicine:
    • distinguish nuclear particles,
    • express nuclear activity and Half-life,
    • learn units for measuring nuclear activity,
    • undertand interaction of nuclear particles and matter (alpha particles, beta particles, gamma Rays),
    • express attenuation of gamma radiation,
    • understand generation and detection of nuclear emission: nuclear sources, radionuclide generators, nuclear radiation detectors, collimators,
    • understand operation principles of radionuclide imaging systems: rectilinear scanner, scintillation scanner, single photon emission tomography, positron emission tomography Internal radiation dosimetry and biological effects. 
  • understand the fundamentals of magnetic resonance imaging:
    • express angular momentum, magnetic dipole moment, magnetization, Larmor frequency, rotating frame of reference and the RF magnetic field, Free Induction Decay (FID), Fourier Spectrum of the NMR signal, Spin Density, Relaxation Times,
    • learn existing Pulse Sequences,
    • understand generation and detection of NMR signal: the magnet, magnetic field gradients, the NMR coil/probe, data acquisition.
    • undertand principles of Imaging methods: slice selection, frequency encoding, phase encoding, spin-echo imaging, and gradient-echo imaging, 
    • learn biological effects of magnetic fields: static magnetic fields, radio frequency fields, gradient magnetic fields. 
  • understand the fundamentals of ultrasound imaging:
    • express stress and strain relationship, equation of motion, characteristic impedance, intensity, radiation force, reflection and refraction, attenuation, absorption, and scattering,
    • understand Doppler effect and Doppler methods,
    • understand generation and detection of ultrasound (piezoelectric effect, ultrasonic transducers, transducer beam characteristics, axial and lateral resolution, focusing, arrays.),
    • understand the operation principles of Ultrasonic Diagnostic methods (pulse-echo systems, ultrasonic transmission methods, and transmission tomography) 
    • comprehend the biological effects of ultrasound.

Program Outcomes Matrix

Contribution
#Program OutcomesNoYes
1An ability to identify, formulate, and solve complex engineering problems by applying principles of engineering, science, and mathematics
2An ability to apply engineering design to produce solutions that meet specified needs with consideration of public health, safety, and welfare, as well as global, cultural, social, environmental, and economic factors
3An ability to communicate effectively with a range of audiences
4An ability to recognize ethical and professional responsibilities in engineering situations and make informed judgments, which must consider the impact of engineering solutions in global, economic, environmental, and societal contexts.
5An ability to function effectively on a team whose members together provide leadership, create a collaborative and inclusive environment, establish goals, plan tasks, and meet objectives
6An ability to develop and conduct appropriate experimentation, analyze and interpret data, and use engineering judgment to draw conclusions
7An ability to acquire and apply new knowledge as needed, using appropriate learning strategies