BIOL769 ADVANCED TOPICS IN IMMUNOLOGY AND CELL BIOLOGY
| Course Code: | 2380769 |
| METU Credit (Theoretical-Laboratory hours/week): | 3 (3.00 - 0.00) |
| ECTS Credit: | 8.0 |
| Department: | Biology |
| Language of Instruction: | English |
| Level of Study: | Graduate |
| Course Coordinator: | Assist.Prof.Dr BANU BAYYURT KOCABAŞ |
| Offered Semester: | Fall Semesters. |
Course Objectives
The course aims to teach recent knowledge about immunology and cellular biology. We will read high impact papers to follow the new informations gained for the last 5 years. First review papers will be discused together and then a related research article will be presented by students. Course subjects include innate immunity, pattern recognition receptors (PRRs), pathogen-damage associated molecular patterns (PAMP and DAMP), RNA-DNA sensors, mitochondrial alarm mechanisms, vault particle, outer membrane vesicles, tight junctions and cytosolic compartments. All subjects are discussed in accordance of immunity. Therefore, the ones who have no immunobiology backgrouond are discouraged to take this course.
Course Content
New and emerging themes in immunology and cell biology with an emphasis on the mechanism of action of recently identified nucleic acid recognition receptors and second messengers. Topics include: cytosolic RNA and DNA sensors, mitochondrial stress and DNA damage related immune responses, gap junctions and their role in host defense, recent advances in inflammasome biology, newly identified cyclic dinucleotide based second messengers and their role in host defense, importance of exonucleases in health and disease, the mystries of vault particles.
Course Learning Outcomes
Recent knowledge about immunology and cellular biology
Able to read high impact papers to follow the new informations gained for the last 5 years.
Program Outcomes Matrix
| Level of Contribution | |||||
| # | Program Outcomes | 0 | 1 | 2 | 3 |
| 1 | Explain the inner workings of the scientific process, discuss critically, and solve problems by applying appropriate statistical and computational methods; choose experimental and theoretical approaches in biology. | ✔ | |||
| 2 | Communicate issues in both English and Turkish with high proficiency. | ✔ | |||
| 3 | Read, and critique scientific communications in biology literature with worldwide recognition. | ✔ | |||
| 4 | Identify and explain issues in biological sciences within the context of other disciplines. | ✔ | |||
| 5 | Readily apply innovative theoretical and technological challenges acting upon the need for lifelong learning. | ✔ | |||
| 6 | Produce data and interpret results as an individual, as well as a team player, and lead whenever necessary. | ✔ | |||
| 7 | Apply and defend the rules of scientific ethics within their careers and professions. | ✔ | |||
0: No Contribution 1: Little Contribution 2: Partial Contribution 3: Full Contribution