BIOL424 CLINICAL BIOCHEMISTRY

Course Code:2380424
METU Credit (Theoretical-Laboratory hours/week):4 (2.00 - 4.00)
ECTS Credit:9.0
Department:Biology
Language of Instruction:English
Level of Study:Undergraduate
Course Coordinator:Prof.Dr. ORHAN ADALI
Offered Semester:Spring Semesters.

Course Objectives

This course consists of a theoretical and a practical laboratory part.

In the theoretical part, a number of concentration units used to prepare solutions are taught. In addition, the constituents of the body fluids such as urine and blood and also the normal level and function of these and how they change in disease cases will be given. Furthermore, the molecular and biochemical basis and clinical consequences of disease cases including diabetes mellitus, jaundice, phenylketonuria and others are going to be taught.

 

In the practical part, experiments are carried out to analyze the constituents of blood serum. These include determination of total protein, albumin, glucose, bile pigments,urea, total lipid, triglycerides, total hemoglobin, total iron as well as enzymes to test the functions of liver and kidney. In addition serum protein electrophoresis technique will be given.


Course Content

The main object of the course is to deal with the quantitative analysis of body fluids such as blood and urine. The changes in the composition of body constituents under pathological conditions are discussed.


Course Learning Outcomes

1. Describe the buffers and explain the importance of blood buffer systems in the regulation of blood pH.

2. List the normal constituents of major body fluids known as urine and blood. 

3. List the techniques and appraoches to study proteins and protein disorders in detail.

4. Explain the functions of liver and describe the biochemical and clinical basis of disease jaundice.

5. Explain the carbohydrate disorders and giving the molecular, biochemical and clinical details of disease diabetes mellitus.

 

 


Program Outcomes Matrix

Level of Contribution
#Program Outcomes0123
1Perform basic laboratory and field techniques/approaches used in various branches of biology.
2Understand and apply principles of laboratory and field safety.
3Understand the inner workings of the scientific processes, think critically, and frame questions using experimental and theoretical approaches in biology.
4Proficiency in communicating issues in both English and Turkish.
5Read, and understand scientific communications from primary literature in biology.
6Identify and explain issues in biological sciences.
7Be ready to take new theoretical and technological challenges by recognizing the value and act upon the need for lifelong learning.
8Work as an individual, as well as a team member, and assume leadship when needed.
9Follow the rules of scientific ethics within their careers and professions.

0: No Contribution 1: Little Contribution 2: Partial Contribution 3: Full Contribution