BIOL407 IMMUNOLOGY

Course Code:2380407
METU Credit (Theoretical-Laboratory hours/week):3 (3.00 - 0.00)
ECTS Credit:6.0
Department:Biology
Language of Instruction:English
Level of Study:Undergraduate
Course Coordinator:Assist.Prof.Dr BANU BAYYURT KOCABAŞ
Offered Semester:Fall or Spring Semesters.

Course Objectives

1. Explain how immune system recognizes “self” and  sense “non-self”,

2. Describe pattern recognition receptors, antigen receptors, MHC molecules, antigen presentation pathways, NK cell receptors and inflammation,

3. Explain how innate immune system operates and its role in activation of adaptive immunity,

4. Describe the process of generation of antigen recognition receptors and explain how B cells and T cells respond to antigen,

5. Describe distinct antigen presentation pathways to T lymphocytes,

6. Describe  signaling through immune system receptors,

7. Describe the process of lymphocyte development and list the factors contributing to survival of lymphocytes,

8. Describe cellular and humoral immunity and explain the dynamics of adaptive immunity.


Course Content

A survey of the immune system and immunological mechanisms. Students are not only introduced to the field of immunology but are also prepared to benefit from their own life time experiences.


Course Learning Outcomes

1. Communicate major scientific principles linking innate and adaptive immunity,

2. Describe common operational principles pertaining to self versus non-self discrimination,

3. Describe how the innate immune system operates,

4. Analyze the generation of antigen recognition receptors and their diversity,

in lymphocytes,

5. Describe how B cells, helper and cytotoxic T cells recognize antigen,

6. Understand the importance of MHC molecules and describe their types and roles in antigen processing and presentation,

7. Understand the dynamics of adaptive immunity,

8. Describe the balance between various T cell types and understand the basics of immune pathology following disruption of this balance,

9. Apply critical thinking and creativity in immunology.


Program Outcomes Matrix

Level of Contribution
#Program Outcomes0123
1Perform basic laboratory and field techniques/approaches used in various branches of biology.
2Understand and apply principles of laboratory and field safety.
3Understand the inner workings of the scientific processes, think critically, and frame questions using experimental and theoretical approaches in biology.
4Proficiency in communicating issues in both English and Turkish.
5Read, and understand scientific communications from primary literature in biology.
6Identify and explain issues in biological sciences.
7Be ready to take new theoretical and technological challenges by recognizing the value and act upon the need for lifelong learning.
8Work as an individual, as well as a team member, and assume leadship when needed.
9Follow the rules of scientific ethics within their careers and professions.

0: No Contribution 1: Little Contribution 2: Partial Contribution 3: Full Contribution