BIOL306 MOLECULAR GENETICS

Course Code:2380306
METU Credit (Theoretical-Laboratory hours/week):3 (3.00 - 0.00)
ECTS Credit:6.0
Department:Biology
Language of Instruction:English
Level of Study:Undergraduate
Course Coordinator:Prof.Dr. AYŞE ELİF ERSON BENSAN
Offered Semester:Spring Semesters.

Course Objectives

To understand the fundamental mechanisms of the living world through molecular biology and genetics


Course Content

This course provides the students with a coherent view of molecular genetics from current perspective. Attention is paid to detailed treatment of gene structure and function (such as chemistry of gene, replication, transcription, translation, regulation of gene expression, gene mutation, and viral genetics), and the recent applications of molecular genetics. Prokaryotic and eukaryotic molecular genetics are given equal weight.


Course Learning Outcomes

Students will have a comprehensive view of how the information flow from DNA to proteins is managed in cells.  The students must recall previously-learned concepts of genetics and build new information on these basic concepts.

The topics we will cover are:

Chapter 4 Content of Genome Chapter 5 Genome  sequences and evolution

Chapter 9,10,11. DNA replication (+ read chapter 10 (Klug) for prokaryotes)

Chapter 13-16. Homologous and site-specific recombination, Somatic DNA recombination

Chapter 14. DNA repair

Chapter 15. Transposable  elements and retroviruses

 

Chapter 18. Eukaryotic transcription (+ read Chapter 17 for prokaryotes)

Chapter 19. Splicing and processing

Chapter 20. mRNA stability and localization

Chapter 21/29. Catalytic RNA and Non-coding RNA

Chapter 22/23. Translation (eukaryotic)

Chapter 26 Eukaryotic gene regulation (+ read Chapter 24 for prokaryotes)

 


Program Outcomes Matrix

Level of Contribution
#Program Outcomes0123
1Perform basic laboratory and field techniques/approaches used in various branches of biology.
2Understand and apply principles of laboratory and field safety.
3Understand the inner workings of the scientific processes, think critically, and frame questions using experimental and theoretical approaches in biology.
4Proficiency in communicating issues in both English and Turkish.
5Read, and understand scientific communications from primary literature in biology.
6Identify and explain issues in biological sciences.
7Be ready to take new theoretical and technological challenges by recognizing the value and act upon the need for lifelong learning.
8Work as an individual, as well as a team member, and assume leadship when needed.
9Follow the rules of scientific ethics within their careers and professions.

0: No Contribution 1: Little Contribution 2: Partial Contribution 3: Full Contribution